The Nvidia Mosaic setup only supports output to an X * Y matrix of screens with similar resolution. Nvidia also recommends that all the screens in a Mosaic video wall should be the same model. From one GPU you can get 4 outputs. It is not recommended to add more GPUs to the computer. The recommended way of combining more screens, and/or different aspects and resolutions, is to use an external video wall display controller, like Datapath Fx4.

The principle is that the Viz Engine draws all its output on one big renderer space, where the different areas are defined by the size and position of the GFX channels. On the hardware side, the output from the GPU (combined with Nvidia Mosaic or not), fed into one or more display controllers, will distribute the pixels to the physical screens.

The screen layout given in Datapath Fx4 controllers can be imported into Viz Multiplay to create Active Areas (snap points) for the GFX channels when designing the walls.

See Using Datapath Fx4 display controller.